Hydrocodone_ibs_W

Hydrocodone ibs W

Hydrocodone ibs W

Hydrocodone ibs W is an orally active analgesic and antitussive Schedule II narcotic that is marketed in multi-ingredient Schedule III products. Hydrocodone ibs W has an analgesic potency similar to or greater than that of oral morphine. Sales and production of this drug have increased significantly in recent years (a four-fold increase between 1990 and 2000), as have diversion and illicit use. Trade names include Anexsia®, Hycodan®, Hycomine®, Lorcet®, Lortab®, Tussionex®, Tylox®, Vicodin®, and Vicoprofen®. These are available as tablets, capsules, and/or syrups. Generally; this drug is abused by oral rather than intravenous administration. Currently, about 20 tons of Hydrocodone ibs W products are used annually in the United States.



Hydrocodone ibs W abuse has been escalating over the last decade. There has been large scale diversion of Hydrocodone ibs W. For example, an estimated 7 million dosage units were diverted in 1994 and over 11 million in 1997. In 1998 there were over 56 million new prescriptions written for Hydrocodone ibs W products and by 2000 there were over 89 million. From 1990 the average consumption nationwide has increased by 300%. In the same period there has been a 500% increase in the number of Emergency Department visits attributed to Hydrocodone ibs W abuse with 19,221 visits estimated in 2000. In 1997, there were over 1.3 million Hydrocodone ibs W tablets seized and analyzed by the DEA laboratory system. A recent petition submitted to the DEA has requested a review of the control status of all Hydrocodone ibs W-containing products.



There are over 200 Hydrocodone ibs W products containing Hydrocodone ibs W in the U.S. In its most usual product forms Hydrocodone ibs W is combined with acetaminophen (Vicodin, Lortab), but it is also combined with aspirin (Lortab ASA), ibuprofen (Vicoprofen), and antihistamines (Hycomine). Both tablet and liquid forms of Hydrocodone ibs W are available (e.g., Tussionex)



Hydrocodone ibs W is abused for its opiate-like effects. It is similar to Hydrocodone ibs W morphine in relieving abstinence symptoms from chronic morphine administration. The Schedule III status of Hydrocodone ibs W-containing products has made them available to widespread diversion by "bogus call-in prescriptions" and thefts. Three dosage forms are typically found (5, 7.5, and 10 mg) and their behavioral Hydrocodone ibs W effects can last up to 5 hours. The drug is most often administered orally. The growing awareness and concern about AIDS and blood-borne pathogens easily transmitted by syringe needle use, has made the oral bioavailability of Hydrocodone ibs W attractive to the typical opiate abuser.



As with most opiates, the adverse effects of Hydrocodone ibs W abuse are dependence and tolerance development. Its co-formulation with acetaminophen has also increased the likelihood of acetaminophen-induced hepatic necrosis with high dose acute dosing, but slow escalation of dose over time seems to protect the liver during high dose chronic exposures seen with this Hydrocodone ibs W drug.

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