CHICAGO (Reuters) – A drug used to protect the kidneys from contrast dye during X-rays of the heart's blood vessels doesn't work, researchers said Tuesday, citing a large study that may change the way patients are treated.The generic drug, acetylcysteine, is made by various companies and marketed under various names.Contrast dye used during coronary arteriograms and angiography procedures may harm kidney function in some patients, especially those older than 70 years and who have had kidney failure, congestive heart failure or diabetes."Some patients need this type of exam to diagnose if they need revascularization, but it's not good enough to fix the heart if it harms the kidneys," said Dr. Otavio Berwanger, lead author of the study and director of the Research Institute at the Hospital do Coracao in Sao Paulo, Brazil.Damage from contrast dye is the second-most common cause of kidney failure in hospitals in Brazil and the third leading cause of kidney failure in U.S. hospitals.In earlier studies, researchers found mixed results on the benefits of using acetylcysteine, a relatively safe and cheap medicine, to shield the kidneys from the contrast dye.In the study of 2,308 patients, 13 percent of those who received acetylcysteine suffered kidney damage after a cardiac X-ray procedure in which dye was used. The rate of kidney damage in patients who took a placebo was also 13 percent.Results were the same in the drug and placebo groups regardless of the type of dye used, the researchers said.The study was funded by Brazil's Ministry of Health and released at the American Heart Association's annual meeting in Chicago."This will inform clinical practice," Berwanger said. "Sometimes you have something implemented in clinical practice that is not useful, even if it is safe and cheap."The researcher said less toxic contrast dyes, or a different compound that can protect the kidneys from dye, are needed.Researchers are also studying the potential of saline as well as bicarbonate to protect the kidneys.(Reporting by Susan Kelly, editing by Lisa Von Ahn)In the mix (IDT) (11 march 2003) album.mp3 Zum.Analyzer volume 3 mp3 albums.Can't Stop Now mp3 albums.La Familia mp3 albums downloads
Drug fails to protect kidneys from X-ray dye-study
CHICAGO (Reuters) – A drug used to protect the kidneys from contrast dye during X-rays of the heart's blood vessels doesn't work, researchers said Tuesday, citing a large study that may change the way patients are treated.The generic drug, acetylcysteine, is made by various companies and marketed under various names.Contrast dye used during coronary arteriograms and angiography procedures may harm kidney function in some patients, especially those older than 70 years and who have had kidney failure, congestive heart failure or diabetes."Some patients need this type of exam to diagnose if they need revascularization, but it's not good enough to fix the heart if it harms the kidneys," said Dr. Otavio Berwanger, lead author of the study and director of the Research Institute at the Hospital do Coracao in Sao Paulo, Brazil.Damage from contrast dye is the second-most common cause of kidney failure in hospitals in Brazil and the third leading cause of kidney failure in U.S. hospitals.In earlier studies, researchers found mixed results on the benefits of using acetylcysteine, a relatively safe and cheap medicine, to shield the kidneys from the contrast dye.In the study of 2,308 patients, 13 percent of those who received acetylcysteine suffered kidney damage after a cardiac X-ray procedure in which dye was used. The rate of kidney damage in patients who took a placebo was also 13 percent.Results were the same in the drug and placebo groups regardless of the type of dye used, the researchers said.The study was funded by Brazil's Ministry of Health and released at the American Heart Association's annual meeting in Chicago."This will inform clinical practice," Berwanger said. "Sometimes you have something implemented in clinical practice that is not useful, even if it is safe and cheap."The researcher said less toxic contrast dyes, or a different compound that can protect the kidneys from dye, are needed.Researchers are also studying the potential of saline as well as bicarbonate to protect the kidneys.(Reporting by Susan Kelly, editing by Lisa Von Ahn)In the mix (IDT) (11 march 2003) album.mp3 Zum.Analyzer volume 3 mp3 albums.Can't Stop Now mp3 albums.La Familia mp3 albums downloads