What is the all-meat diet? Does science back it?

In the world of diets, the all-meat diet has become a subject of curiosity and controversy. Also known as the carnivore diet, this nutritional approach goes against the grain by advocating for a diet exclusively composed of animal products. In this short article, we’ll take a quick look at what the all-meat diet entails, its potential benefits, and the debates surrounding its adoption. Whether you’re a seasoned nutrition enthusiast or just curious about the latest dietary trends, let’s unravel the basics of the all-meat diet together.

What is the all-meat diet?

The All-Meat Diet, or the carnivore diet, is a highly restrictive eating plan that exclusively includes meat, fish, and certain animal products such as eggs and select dairy items. This diet explicitly excludes all other food categories, such as fruits, vegetables, legumes, grains, nuts, and seeds.

Adherents of the All-Meat Diet advocate for eliminating or reducing dairy consumption, with a preference for low-lactose options like butter and hard cheeses. The underlying philosophy of this diet traces back to the controversial belief that ancestral human populations primarily consumed meat and fish and attributes modern chronic diseases to high-carbohydrate diets.

Dr. Shawn Baker, a prominent supporter of the carnivore diet and an American orthopedic doctor, often highlights anecdotal evidence from followers claiming positive outcomes such as improved mental health, weight loss, and relief from conditions like depression, anxiety, arthritis, and diabetes.

Because of these testimonials, I would like to point out that no controlled studies have been conducted to analyze the carnivore diet’s effects rigorously. A study associated with Baker, relying on self-reported data from diet followers, lacks objective measures and raises concerns among nutrition experts. Notably, the study’s findings lack verifiability, cautioning against definitive interpretations.

Additionally, it is worth mentioning that Dr. Shawn Baker faced professional challenges in 2017 when the New Mexico Medical Board revoked his medical license due to competency concerns. While his license was reinstated in 2019, it came with a stipulation for direct supervision during medical practice. This information adds a layer of context to consider when evaluating the credibility of the diet’s proponents.

How to Adopt the Carnivore Diet

To start the carnivore diet, one must exclude all plant-based foods and focus solely on consuming meat, fish, eggs, and limited quantities of low-lactose dairy products.

Permissible food options encompass beef, chicken, pork, lamb, turkey, organ meats, salmon, sardines, white fish, and modest portions of heavy cream and hard cheese. Butter, lard, and bone marrow are also permitted.

Advocates of the diet stress the importance of incorporating fatty cuts of meat into one’s daily consumption to meet energy requirements.

While on the carnivore diet, individuals are encouraged to hydrate with water and bone broth, with a discouragement of tea, coffee, and other plant-based beverages.

Notably, carnivore diet plans may lack specific guidance on calorie intake, serving sizes, or meal frequency. Most proponents suggest eating according to personal appetite without strict prescriptions on these details.

In summary, the carnivore diet entails the exclusive consumption of meat, fish, and animal products, with limited information on calorie management, serving sizes, and meal timing.

Benefits and risks of carnivore diet

The carnivore diet, which involves consuming only animal products and excluding plant foods, has proponents who claim various benefits. However, it’s important to note that the scientific evidence supporting these claims is limited, and potential risks and side effects should be considered.

Potential Benefits

  1. Weight Loss: Some individuals report weight loss on the carnivore diet, which may be attributed to reduced calorie intake and increased satiety from protein-rich foods.
  2. Simplicity: The diet is straightforward and eliminates the need for complex meal planning involving a variety of foods.
  3. Nutrient Density: Animal products are rich in essential nutrients such as protein, vitamins, and minerals.
  4. Digestive Issues: For some people with digestive issues or autoimmune conditions, eliminating certain plant foods may alleviate symptoms.

Potential Risks and Side Effects

  1. Nutrient Deficiencies: Excluding plant foods may lead to deficiencies in certain vitamins, minerals, and fiber abundant in fruits and vegetables.
  2. Digestive Discomfort: Some individuals may experience constipation or other digestive issues due to the lack of fiber in the diet.
  3. Long-Term Health Risks: The long-term health effects of the carnivore diet are not well-studied, and potential risks, especially in heart health and bone health, are unclear.
  4. Lack of Fiber: The absence of fiber from plant foods may negatively impact gut health and increase the risk of certain diseases.
  5. Sustainability: The environmental impact of a diet based solely on animal products is a concern, as plant-based diets are generally considered more sustainable.
  6. Cholesterol Levels: Some studies suggest high red and processed meat consumption may be associated with increased cholesterol levels and cardiovascular risk.
  7. Lack of Variety: The restrictive diet may lead to monotony and a lack of dietary variety, potentially limiting exposure to various nutrients.

Does science back the all-meat diet?

The all-meat or carnivore diet, characterized by the exclusive consumption of animal products and the exclusion of plant-based foods, has been associated with reported benefits and potential risks. Proponents suggest that adherents may experience weight loss due to reduced carbohydrate intake, leading to lower insulin levels and increased fat burning.

This article focuses on a meta-analysis comparing the effects of low-carbohydrate diets (≤45% of energy from carbohydrates) versus low-fat diets (≤30% of energy from fat) on metabolic risk factors.

Additionally, some individuals find the simplicity of the diet appealing, as it involves consuming meat, fish, and animal fats exclusively. Some proponents also claim improved mental clarity and focus while following the carnivore diet. However, it’s crucial to note that scientific evidence supporting these claims is limited, and individual responses to the diet can vary widely.

Despite reported benefits, concerns and potential risks are associated with the all-meat diet. Excluding plant-based foods may lead to nutrient deficiencies, particularly in essential vitamins, minerals, and fiber abundant in fruits and vegetables.

The absence of dietary fiber from plant sources could impact digestive health, potentially leading to constipation. Moreover, the high consumption of red and processed meats, a key component of the carnivore diet, has been linked to an increased risk of chronic diseases, including heart disease and certain cancers.

Conclusion

As we wrap up our exploration of the all-meat diet, it’s evident that this carnivorous lifestyle has stirred the pot of dietary discussions. While some swear by its potential benefits, others approach cautiously, mindful of potential nutritional gaps. The all-meat diet, emphasizing animal products and excluding plant-based foods, continues to captivate interest, challenging conventional notions of balanced nutrition.

Whether one sees it as a radical departure or a bold experiment, the all-meat diet underscores the diversity in approaches to health and wellness. As with any dietary choice, individuals must consider their unique needs, consult with healthcare professionals, and make informed decisions.

Antimicrobial Drugs – Part 5: Antifungal and Antiviral Drugs

  1. Antifungal Drugs

(I) Classification of Fungal Infections

Superficial Fungal Infections

Commonly caused by dermatophytes, with fungi such as ringworm affecting the skin, feathers, hair, nails, combs, etc., causing conditions like tinea corporis. Some can be transmitted between humans and animals.

Deep Fungal Infections

Pathogens include Candida and Aspergillus, affecting deep tissues and organs, causing inflammation, necrosis, or abscess formation. Examples include candidiasis, aspergillosis in chicks, fungal uterine infections in cows, and fungal gastroenteritis in calves. These infections pose a risk to internal organs and can be life-threatening(sources from therapeutique-dermatologique).

(II) Types of Antifungal Drugs

Antifungal Drugs: Medications that inhibit or kill the growth or reproduction of fungi.

Classification of Antifungal Infections

★ First Category

(1) Antibiotic Class: Amphotericin B, griseofulvin, nystatin.

(2) Imidazole Class: Ketoconazole, clotrimazole, fluconazole.

(3) Allylamine Class: Terbinafine.

(4) Pyrimidine Class: Flucytosine.

★ Second Category

(1) Systemic Antifungal Drugs

(2) Topical Antifungal Drugs

(III) Systemic Antifungal Agents

Amphotericin B (Amphocin)

(1) Polyene antibiotic, systemic antifungal.

(2) Pharmacokinetics: Poor absorption orally or intramuscularly; slow intravenous administration (IV) for treating systemic fungal infections. Mostly excreted slowly through the kidneys.

(3) Pharmacological Action: Broad-spectrum antifungal, the preferred drug for treating deep fungal infections.

(4) Clinical Application:

① IV Infusion: Effective for treating deep fungal infections such as canine histoplasmosis, sporotrichosis.

② Oral: Poor absorption, used for intestinal fungal infections like candidiasis; topical application for treating superficial fungal infections (skin, nails, etc.).

(5) Adverse Reactions:

① IV administration may cause shaking, high fever, vomiting, leading to liver and kidney damage, anemia, leukopenia, etc. → Slow IV infusion, avoid drip administration.

② Avoid concurrent use with aminoglycosides, digitalis, thiazide diuretics, etc.

Ketoconazole

(1) Pharmacokinetics: Easily absorbed orally.

(2) Pharmacology: Broad-spectrum antifungal effective against both systemic and superficial fungi. Strong inhibitory and fungicidal effects on Blastomyces, Cryptococcus, Candida, Aspergillus, Microsporum, and Trichophyton.

(3) Clinical Application:

① Systemic fungal infections caused by sensitive fungi: oral administration for systemic mycoses in dogs and cats.

② Fungal skin diseases: Topical application.

(IV) Topical Antifungal Drugs

Nystatin

(1) Pharmacokinetics: Easily absorbed orally, widely distributed in various tissues, with high concentrations in the skin, hair, nails, liver, fat, and muscles. Ineffective when applied topically due to poor penetration of the epidermal stratum corneum. → Administered orally, reaching the skin surface through the bloodstream.

(2) Pharmacology: Orally, it has a potent inhibitory effect on various skin fungi (Microsporum, Epidermophyton, and Trichophyton) and is ineffective against other fungi.

(3) Application: Used for various skin fungal infections caused by Microsporum, Epidermophyton, and Trichophyton (dermatophytes).

(4) Adverse Reactions: Teratogenic, carcinogenic; contraindicated in pregnant animals.

Griseofulvin

(1) Acts similarly to Amphotericin B but with greater toxicity, not used for systemic infections.

(2) Gastrointestinal Tract: Poor absorption orally, used for treating gastrointestinal fungal infections (secondary infections), such as avian aspergillosis, candidiasis, and calf fungal gastritis.

(3) Topical: Applied to the skin and mucous membranes for treating skin and mammary gland fungal infections caused by Candida and Aspergillus.

(4) Lungs: Excellent efficacy when inhaled as an aerosol for pulmonary fungal infections.

Clotrimazole

(1) Imidazole broad-spectrum antifungal, low toxicity, minimal risk of resistance.

(2) Similar action against superficial fungi as griseofulvin, less effective against deep fungi than Amphotericin B.

(3) Primarily used topically for superficial skin fungal infections (e.g., ear infections, ringworm), orally for treating deep fungal infections.

  1. Antiviral Drugs

(I) Overview

Viral diseases are primarily prevented by vaccines, and reliable, effective drugs against viruses are still lacking(quotes from therapeutique-dermatologique.org).

Some antiviral drugs used in veterinary clinics have limited applications, lack systematic and formal research data, and are challenging to comprehensively evaluate.

Not recommended or prohibited for food animals due to the potential for developing viral resistance, leading to the depletion of therapeutic resources for human viral diseases.

In pet viral infections, some antiviral drugs can be tested.

(II) Clinically Testable Drugs

Amantadine

Narrow-spectrum drug, interferes with the entry of certain RNA viruses (paramyxoviruses, orthomyxoviruses), inhibits virus uncoating and nucleic acid release, and suppresses viral replication. Highly selective for type A influenza viruses, e.g., avian influenza.

Amikacin (Virazole)

Broad-spectrum, inhibitory against DNA viruses such as adenovirus, Marek’s disease virus, avian poxvirus, avian infectious bronchitis virus; RNA viruses such as influenza virus, paramyxovirus, and avian respiratory coronavirus. Can be used for prevention and treatment of canine distemper and canine parvovirus.

Ribavirin (Virazole, Copegus)

Broad-spectrum antiviral, inhibits both RNA and DNA viruses. Effective against influenza virus, paramyxovirus, herpesvirus, poxvirus, Newcastle disease virus, vesicular stomatitis virus, and foot-and-mouth disease virus. Used for prevention and treatment of canine distemper, canine parvovirus, and feline coronavirus.

Acyclovir (Zovirax)

A synthetic purine nucleoside analog. Mainly used for various infections caused by herpes simplex virus, such as herpetic keratitis (topical), or shingles infection (systemic).

Why is Topical Medication Preferred for Antifungal Infections?

With the increasing environmental changes and severe air pollution, the factors causing skin diseases have multiplied, leading to a significant rise in the incidence of skin diseases. The World Health Organization has declared that skin diseases will be the most prevalent, disabling, and highly infectious diseases in human history in the 21st century.

Fungal infection is a significant cause of skin diseases:

Among the various factors causing skin diseases, fungal infections have long been a major concern for a large number of dermatology patients. Diseases caused by fungal infections can be categorized into superficial and deep fungal infections, depending on the location of fungal invasion into the human body.

Superficial fungal infections involve the skin’s epidermis and its appendages, such as the common areas like hair, skin surface, and nails. Conditions like ringworm, athlete’s foot, and nail fungus are the most widespread examples of superficial fungal diseases. On the other hand, deep fungal infections go beyond the skin and subcutaneous tissues, affecting internal organs and tissues, potentially causing disseminated fungal infections (quotes from therapeutique-dermatologique.org ).

Antifungal treatment: Topical medications are the first choice.

In the realm of dermatological treatments, the market share for antifungal drugs and anti-itch drugs for skin use is close to 50%. In clinical practice, the treatment of superficial fungal infections often follows the principle of “topical treatment first, oral treatment later.” This means that after the onset of the disease, treatment initially relies on topical medications. If the results are unsatisfactory or there is no improvement over time, oral medications are then considered.

Why are topical medications preferred?

This is mainly because the choice of the most effective treatment for fungal infections depends on whether it is a “superficial fungal infection” or a “deep fungal infection.” If it is a deep fungal infection, oral antifungal medications are necessary. Common topical antifungal drugs generally do not have a significant effect on the treatment of deep fungal infections.

For superficial fungal infections, where the fungus is on the skin surface, the use of topical antifungal drugs is more targeted and effective against the disease. Additionally, topical medications are usually applied directly to the affected area, bypassing the body’s bloodstream, resulting in fewer side effects.

In recent years, although there has been significant progress in antifungal drug research, the difficulty in systemic fungal treatment remains a challenge. Addressing drug resistance and adverse reactions is still a focus of research for major pharmaceutical companies. Common antifungal drug formulations on the market include creams, ointments, tablets, capsules, gels, and topical solution, among which creams, ointments, and tablets are widely used and dominate the market (sources from therapeutique-dermatologique ).

Topical medications have a broad application range and are suitable for a wide range of people, with lower difficulty in use. Different formulations of topical drugs play a unique role in the treatment of skin diseases, providing rapid anti-inflammatory, anti-itch, and antimicrobial effects. Therefore, it is believed that in the future dermatological drug market, topical medications will continue to dominate.

Can ‘lichen’ also grow on the human body? Let’s discover together about lichen planus!

Hearing about “lichen planus” might sound strange: how is it possible for it to grow on the human body? The “lichen planus” that grows on the human body is not the same as the “lichen” that grows on the ground! Listen to me as I explain it slowly.

What is lichen planus?

Lichen planus is actually a chronic inflammatory skin disease that primarily affects the skin, hair follicles, mucous membranes, fingers (and toes), with a prevalence in the population of 1.4% – 0.8%. The cause of this disease is unknown, but it could be related to immunological, genetic, viral infections, psychological and neurological factors, and more (sources from therapeutique-dermatologique.org ).

What are the symptoms of lichen planus?

Skin changes: Commonly localized on wrists, around ankles, inside thighs, and on the front of legs. Skin lesions often appear as flat, polygonal, red-violet papules, with white reticular streaks, a wax-like shiny surface, ranging in size from the tip of a pencil to a centimeter, which can be grouped or scattered, localized or widespread, accompanied by itching.

Changes in oral mucosa: The typical appearance involves slightly raised white streaks on the cheeks, intertwined to form a network or short radial elevations. Gums can be involved, manifesting as chronic desquamative gingivitis with evident peeling, swelling, and pain, sometimes accompanied by a feeling of discomfort to severe pain.

Changes in genital areas: Lesions similar to those on oral mucous membranes, ranging from clustered papules to severe ulcerative or erosive lesions.

Changes in fingernails (and toenails): Nail deformities, nail detachment, longitudinal grooves in the nails, wing-shaped hypertrophy, thinning, and even nail damage or detachment.

Hair changes: Hair thinning, hair loss, scalp peeling, with the presence of red-violet follicular papules and itching. In severe cases, permanent scarring hair loss can occur.

Manifestations of special types of lichen planus: Pigmented lichen planus mainly appears as blue pigmented deposits or brown spots on the face, neck, and upper back; vesicular lichen planus presents as a typical form of lichen planus but with blisters or bullae.

What are the risks associated with lichen planus?

Increased risk of cutaneous squamous cell carcinoma, especially in cases of ulcerative lichen planus that develops in the oral cavity, on the feet or genital organs, and in cases of hypertrophic lichen planus on the legs.

Lichen planus of oral mucosa can compromise the ability to eat, making the mucosa sensitive to stimuli, increasing the likelihood of oral inflammations, and severely affecting daily life.

Lichen planus of the ear canal, if not treated promptly, can lead to hearing loss.

How is lichen planus treated?

Currently, there is no specific cure for lichen planus, so an integrated therapeutic approach is often used. If the cause is known or if there are identifiable triggering factors, such as medications or chronic disease foci, it is important to promptly remove such causes.

Treatment modalities for lichen planus include: pharmacological treatment, physical treatment, photodynamic therapy.

Pharmacological treatment mainly involves the topical or oral use of corticosteroids, immunosuppressants, antibiotics, retinoic acid, and other drugs. Physical treatment includes laser therapy, cryotherapy, radiotherapy, and photodynamic therapy. Generally, surgical interventions are not necessary to treat this disease.

Chronic ulcerative lichen planus in the oral mucosa or vulva, or ulcerative lichen planus on the sole of the foot, increases the risk of cutaneous squamous cell carcinoma. Therefore, it is advisable to undergo prompt photodynamic therapy, with a frequency of once a week for 4-6 weeks.

Is it possible not to treat lichen planus?

This disease has a chronic progression, and if not treated promptly, although cutaneous lichen planus usually resolves spontaneously within 1-2 years, it can leave residual pigmentation; involvement of the oral mucosa can sometimes resolve within 5 years but often recurs; hair loss caused by lichen planus is permanent. Additionally, lichen planus has a prolonged duration, impacting the quality of life, mental health, the patient’s outward appearance, and in rare cases, it can evolve into carcinoma, posing a risk to the patient’s life (quotes from therapeutic dermatologique ) .

If treated promptly with regular care, it is possible to effectively control the disease, improve the patient’s quality of life and longevity, reduce scar formation, residual pigmentation, and reduce the risk of developing malignant tumors.

In summary, if lichen planus develops, it is essential to undergo active treatment!

Discover the Power of Legal Steroids in Australia!

Are you ready to take your fitness journey to the next level? Say goodbye to limitations and embrace the epitome of strength and muscle growth with this Steroids in AU guide – the ultimate source for buying legal steroids online.

What are legal steroids?

Legal steroids, also known as legal anabolic steroids or steroid alternatives, are dietary supplements formulated to mimic the effects of traditional anabolic steroids without the associated legal and health risks. Anabolic steroids are synthetic versions of the male sex hormone testosterone, and they are often used to promote muscle growth, increase strength, and improve athletic performance.

Unlike illegal anabolic steroids, which are controlled substances and require a prescription for medical use, legal steroids are typically made from natural ingredients and are available over-the-counter without a prescription. They are regulated as dietary supplements and are generally considered safe for use when taken as directed.

Uses of Legal Steroids

The primary purpose of legal steroids is to provide athletes, bodybuilders, and fitness enthusiasts with a safer and legal alternative to traditional anabolic steroids. They are often used to:

Promote Muscle Growth

Legal steroids can stimulate protein synthesis, leading to increased muscle mass and size.

Enhance Strength and Performance

These supplements may help improve athletic performance, endurance, and overall physical strength.

Accelerate Recovery

Legal steroids may aid in reducing muscle fatigue and promoting faster recovery after intense workouts.

Boost Testosterone Levels

Some legal steroids contain natural ingredients that support healthy testosterone production.

Improve Body Composition

Legal steroids can help reduce body fat and improve muscle definition, leading to a more sculpted physique.

Why Use Legal Steroids over Anabolic Steroids in Australia?

Using legal steroids over anabolic steroids like Anavar offers several advantages, making them a more appealing and safer option for individuals seeking to enhance their performance, muscle growth, and overall fitness. Here are some reasons why one might choose legal steroids over anabolic steroids:

Legal Status

Legal steroids are available over-the-counter as dietary supplements, while anabolic steroids are often classified as controlled substances and require a prescription. By opting for legal steroids, individuals can avoid legal issues and potential penalties associated with the use of illegal substances.

Safety

Legal steroids are generally made from natural ingredients, reducing the risk of severe side effects often associated with anabolic steroids. Illegal steroids can lead to a range of health issues, including liver damage, hormonal imbalances, cardiovascular problems, and more.

No Prescription Required

Legal steroids do not require a prescription or medical supervision, making them more accessible to individuals who wish to enhance their fitness goals without having to visit a healthcare professional.

Quality Assurance

Reputable manufacturers of legal steroids as Anadrol UK site says ensure their products undergo rigorous testing and adhere to strict quality standards. This provides consumers with more confidence in the safety and efficacy of the supplements they are using.

Less Risk of Abuse

Anabolic steroids are sometimes misused and abused by athletes and bodybuilders in higher doses than recommended, leading to serious health consequences. Legal steroids typically have clear dosing instructions, reducing the risk of abuse.

Fewer Hormonal Disruptions

Anabolic steroids can disrupt the body’s natural hormonal balance, leading to unwanted side effects, including changes in mood, libido, and fertility. Legal steroids aim to mimic the benefits of anabolic steroids without causing severe hormonal disruptions.

Available without Needles

Many anabolic steroids are administered through injections, which can be uncomfortable and carry additional risks. Legal steroids, on the other hand, are often available in convenient pill or capsule forms.

Wider Selection of Products

Legal steroid alternatives come in various formulations, catering to specific fitness goals, such as muscle gain, fat loss, endurance, or strength. This allows individuals to choose the most suitable supplement for their needs.

Athletic Organization Compliance

Athletes subject to drug testing can use legal steroids without fear of failing drug tests. These supplements are typically formulated to be undetectable in standard drug tests.

Where to buy legal steroids?

The availability of legal steroids may vary depending on your country’s regulations and laws regarding dietary supplements. It’s essential to note that the supplement market is constantly evolving, and new products and suppliers may emerge over time.

To buy legal steroids, consider the following options:

Online Retailers

Many reputable online retailers specialize in selling legal steroids and other dietary supplements. Search for well-known and established websites that offer a wide range of products, have positive customer reviews, and provide detailed information about their products.

Official Manufacturer Websites

Some legal steroid brands have their official websites where they sell their products directly to customers. Purchasing from the manufacturer’s website ensures the authenticity of the product.

Health and Fitness Stores

Some physical health and fitness stores or supplement Winstrol shops may carry legal steroids. Check with local stores in your area to see if they stock these products.

Sports Nutrition Stores

Specialty sports nutrition stores often carry a selection of legal steroids and performance-enhancing supplements.

Gyms and Fitness Centers

Some gyms and fitness centers may have a small inventory of legal steroids or can provide recommendations on where to purchase them.

Amazon and other Ecommerce Platforms

Large e-commerce platforms like Amazon may have legal steroid products from various sellers. When purchasing from such platforms, be sure to read reviews and check the seller’s credibility.