EBM, una branca della Medicina che si propone di facilitare le decisioni diagnostiche e terapeutiche, con risvolti anche nella gestione delle risorse economiche

Fecal microbiota transplantation is effective in treating relapsing or refractory Clostridium difficile infection

Fecal microbiota transplantation ( FMT ) has been shown to be effective in treating relapsing or refractory Clostridium difficile infection, but practical barriers and safety concerns have prevented i …

Influenza: Oseltamivir modestly reduces the time to first alleviation of symptoms, but it can cause harms

A systematic review of regulatory information has described the potential benefits and harms of Oseltamivir ( Tamiflu ) by reviewing all clinical study reports ( or similar document when no clinical s …

No evidence that Zanamivir reduces the risk of complications of influenza

A systematic review of clinical study reports of randomised placebo controlled trials and regulatory information has described the potential benefits and harms of Zanamivir ( Relenza ). Main outcom …

Triclosan-coated PDS Plus does not reduce the occurrence of surgical site infection after elective midline laparotomy

Postoperative surgical site infections are one of the most frequent complications after open abdominal surgery, and Triclosan-coated sutures were developed to reduce their occurrence. The aim of the …

Influenza vaccine in older adults: efficacy of high-dose versus standard-dose

As compared with a standard-dose vaccine, a high-dose, trivalent, inactivated influenza vaccine ( IIV3-HD ) improves antibody responses to influenza among adults 65 years of age or older. This study …

Hepatitis C: new, short-duration, simpler therapies result in high SVR rates for HCV-infected patients

Hepatitis C virus ( HCV ) infects more than 185 million individuals worldwide. Twenty percent of patients chronically infected with HCV progress to cirrhosis. New, simpler therapeutics using direct-ac …